![]() The system calculated personalized infusion rates based upon each participant's age, height, weight and gender and was programmed so they would reach a target blood alcohol concentration of. The two studies both used an alcohol clamp technique, where participants received an intravenous infusion of alcohol at a rate controlled by a computer-assisted system. On average, the group with obesity had 52.3 kg of lean mass, compared with 47.5 kg for the normal weight group. Based on their BMI, those in the subsample were divided into three groups: normal weight, which included women with BMI ranging from 18.5–24.9 overweight, those with BMI ranging from 25–29.9 and obese, participants with BMI above 30.Īs the researchers expected, women with higher BMI had not only more fat mass than women of healthy weights, they also had more lean mass. In a subsample of 102 of these women, the researchers had measured the proportions of lean and fat tissue in their bodies and calculated their body mass indices. Among these were 19 women who had undergone different types of bariatric surgery. The combined sample from the studies used in the analysis included 143 women who ranged in age from 21 to 64 and represented a wide range of body mass indices-from healthy weights to severe obesity. Both projects used similar methods to estimate the rate at which alcohol is broken down in the body. To explore links between body composition and alcohol elimination rates, the team conducted a secondary analysis of data from a study performed at the U of I and another at Indiana University, Indianapolis. Yanina Pepino, a professor of food science and human nutrition at the University of Illinois Urbana-Champaign. ![]() "We believe the strong relationship we found between participants' lean body mass and their alcohol elimination rate is due to the association that exists between lean body mass and lean liver tissue-the part of the liver responsible for metabolizing alcohol," said research group leader M. ![]() ![]() The research is published in the journal Alcohol: Clinical and Experimental Research. ![]()
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